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With the boost up in the pace of living and stress, several civilized diseases have come into play worldwide. Constipation is one of the most common gastrointestinal disorders, estimated to affect 15% of the worldwide population. Taking medicinal therapies for metabolic, neurological, and endocrine disorders have also been known to cause constipation. An estimated 2.5 million doctor visits stemming from chronic constipation was reported in the US with 85% of the patients subsequently receiving a prescription for therapy.
STD07, a single component purified from an herb, is under development for the treatment of gastrointestinal disorders such as constipation and Irritable Bowel Syndrome (IBS). STD07 is an active ingredient of a plant that has been widely used as food additive or traditional herbal medicine in China and several European countries. Historical applications of this plant include stool softener, blood pressure lowering, and improving renal function. STD07, a patented component, was thus purified and is under development for prolonged usage to maintain normal GI motility and disorders such as constipation and IBS. Animal pharmacology studies showed that oral dose of STD07 resulted in significant increase of water-holding capacity, bowel movement, and bulk fecal excretion in rat model.
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